Whilst gastrointestinal side effects are well documented, some patients report sleep disturbances, including insomnia, during treatment
This caution comes mainly from cosmetic formulators rather than from dermatology trials, and the evidence is limited, so it is not something to state as a hard rule
Neurological and anti-inflammatory effects: Shows promise in Alzheimers disease and neuroprotection
Gradual weight loss is also recommended to avoid complications that can arise from rapid weight reduction, such as bile duct stones
In men, obesity is associated with lower testosterone levels due to increased conversion of testosterone to oestrogen in fat tissue, and this can contribute to reduced libido and erectile dysfunction
doi: 10.1046/j.1365-2265.1996.726547.x 45 AttiaNCaprioSJonesTWHeptullaRHolcombeJSilverDet al