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When used thoughtfully and paired with lifestyle interventions, GLP-1 medications can support healthy aging while minimizing the risk of excessive muscle loss

However, incomplete removal results in recurrence that may envelop the previous biopsy, excision, or treatment site and interfere with histologic evaluation

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A phase 2 trial (NCT05063539) was initiated in September 2021 for assessing the safety, tolerability, and efficacy of LY3372689 in 330 patients with early symptomatic AD with progressive memory changes for 6 months and who met the criterion of having a positive flortaucipir-PET scan

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