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doi: 10.1038/s41467-024-49655-6

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Normally, when you eat, GLP-1 is released naturally and has the following actions: Signals the stomach to release food slowly Stimulates the pancreas to stop releasing glucagon, and start releasing insulin to prepare for a spike in blood sugar (Eventually) travels to the brain and acts on several areas involved in appetite regulation, shutting down the desire for food These are powerful effects, but they are tempered by the fact that GLP-1 doesnt stick around for very long

But I think we just need to observe people

Below 0.1 indicates significant suppression that requires prompt dose reduction