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Ethical principles of the study complied with the European Directive 010/63/E, the Law on Amendments to the Animal Protection Act (Official Gazette 37/13), the Animal Protection Act (Official Gazette 135/06), the ordinance on the protection of animals used for scientific purposes (Official Gazette 55/13), Federation of European Laboratory Animal Science Associations (FELASA) recommendations, and the recommendations of the Ethics Committee of the School of Medicine, University of Zagreb
This finding could be explained by a competition among selenoproteins for available selenium in the form of selenocysteine required for biosynthesis of the selenoproteins and for the selenium-incorporation machinery
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In addition, it has been shown that SAG pretreatment significantly prevents CCl4-induced cytotoxicity, is protective in restoring mitochondrial autophagy, and attenuates fibrosis, collagen deposition, hepatocellular damage and organ dysfunction
Women need to keep in mind though that this is not a perfect birth control
