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Symptomatic relief can be achieved with over-the-counter treatments such as: Benzydamine mouthwash or spray for pain relief Protective gels containing hyaluronic acid or carmellose to coat ulcers Chlorhexidine mouthwash to reduce secondary bacterial infection (use short-term only, typically for 7 days, as it can cause staining and taste disturbance

However, blocking GLP-1R did not improve CM-related hypersensitivity

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Understanding the complete side effect profile enables informed decision-making and appropriate symptom management

Moreover, excess copper can directly oxidize glutathione, leading to its depletion

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