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Both in vitro and in vivo studies have shown that diNACA prevents cataract formation by regulating mixed disulfide formation but not by increasing glutathione synthesis

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J Bacteriol 103:475478 Genghof DS, van Damme O (1964) Biosynthesis of ergothioneine and hercynine by mycobacteria

While high sheer stress caused by vasoconstriction is considered atheroprotective during the early phases of atherogenesis, it later predisposes individuals to more vulnerable plaque phenotypes that cause MI and stroke 42

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"We're seeing a perfect storm," GP Dr Mike Mrozinski explains