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As these non-invasive surrogate measures of ICP have not been validated against the gold standard invasive direct measures of ICP, the diagnostic and monitoring capabilities of these non-invasive tests remain uncertain and the established normative values are lacking
For those interested in understanding their individual response to semaglutide, PlexusDx's Precision Peptide Genetic Test maps fourteen metabolic pathways, including GLP1R variants like rs6923761, which influence how your body responds to GLP-1 activation
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An exploratory mediation analysis of stroke outcomes in the REWIND CVOT, in which dulaglutide reduced systolic blood pressure (SBP) by a mean of 1.7 mmHg compared to placebo, found that the blood pressure reduction caused by dulaglutide accounts for around 14% of its effect on stroke risk [21]
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