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7,8,64 NAMPT facilitates increases in CSC pools, suggesting that the CSCs in tumors primarily use the NAD salvage pathway to maintain a full, rich source of nutrients for enzymatic activity, leading to tumor progression and the eventual reprogramming of mature tumor cells, which finally results in therapy resistance, relapse, and metastasis

In a family with retinoblastoma and multiple lipomas, the lipomas were present in people with a gene mutation in the RB1 gene who did not develop retinoblastomas (158)

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Asadi A, Ghahremani R, Abdolmaleki A, Rajaei F