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Reconstitution is the process of converting a lyophilised (freeze-dried) peptide into a liquid solution for laboratory use by adding a suitable sterile diluent, such as Bacteriostatic (BAC) Water or sterile water intended for research applications

However, "stronger" also means stronger side effects, with discontinuation rates of 12-18% for retatrutide versus 5-7% for semaglutide

Maliphol AB, Garth DJ, Medler KF

The medication is started at a low dose and titrated up slowly to allow the body to tolerate the medication while minimizing side effects

Retatrutide is the logical choice for women who want maximum fat loss outcomes and are willing to manage a more demanding titration process with more assertive GI side effect management

It holds no approved indication for anything