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The absorption rate through sublingual tissue may differ significantly from subcutaneous injection, which could affect both the timing and magnitude of therapeutic effects

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The answer is more nuanced than a simple yes or no

That effect only shows up when there is a calorie deficit and activity for it to act on

If you are also interested in how other injectable treatments compare, check out the Mounjaro vs Trulicity comparison for more context on weekly injectables

Commenters also stated that appropriately accounting for research and development costs in Medicare payments would be challenging