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Among the double mutants, only Cla+Arr (6.1%) presented a difference when compared to WT

Only the first adjudicated MACE event per participant that occurred during the follow-up period (weeks 56104) was included

Motor nerve damage causes muscle weakness, cramping, atrophy, and difficulty with coordination

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This is known as tolerance withdrawal and interdose withdrawal. An estimated 50-80% of people who have taken benzodiazepines continually for a few weeks or longer will experience withdrawal symptoms when reducing the dose

Yu, Y., Liu, L., Wang, X., Liu, X., Liu, X., Xie, L., et al