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Current clinical treatment guidelines aim for a functional cure for CHB, which involves sustained negativity for hepatitis B surface antigen (HBsAg), undetectable HBV DNA, normal liver biochemical indicators, and improvement of liver tissue lesions after treatment cessation

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Sep 13 2021;127(12):1-10

Bloodbrain barrier disruption by lipopolysaccharide and sepsis-associated encephalopathy

Its triple receptor activity makes it particularly valuable for mechanistic investigations involving glucose regulation, nutrient utilization, metabolic flexibility, and energy expenditure

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