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Some patients may require an even higher dose of 2 mg weekly for optimal effect, particularly for weight management indications, though this should be approached cautiously with careful monitoring for adverse effects

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NAION belongs in that mindset

doi: 10.1158/1078-0432.CCR-11-1217 11 GreenCDMaceykaMCowartLASpiegelS

the American Diabetes Association recommends reassessing A1C about every 3 months after therapy changes

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