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Research on interferon -2a and other proteins shows that 0.9% benzyl alcohol can cause aggregation , though effects are concentration-dependent and protein-specific

Warning signs include: Sudden rash or hives spreading across the body Generalized itching that is not isolated to the application site Swelling of the face, lips, tongue, or throat Difficulty breathing or shortness of breath Symptoms suggestive of a severe allergic reaction (anaphylaxis) require prompt medical attention

PLoS One 9 , e92649 (2014)

Jordan LeBel, a food marketing professor at Concordia University, said of that revenue hit, "It doesn't sound like a big number, but that's hundreds of millions of dollars." Analysts already see brand-level risks

Discontinuation rates due to GI side effects range from about 1% to 10.5% across the SURMOUNT trials