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Safety Data Review Across published studies, CJC-1295 has demonstrated a favorable safety profile: Common Adverse Events Injection site reactions (redness, swelling, pain): the most frequently reported side effect Headache: mild and transient Diarrhea: reported in some subjects, particularly at higher doses Flushing: transient warmth or redness Dizziness: occasional and brief Serious Adverse Events One serious adverse event in the early clinical development program, a death that occurred in a subject during a study, drew attention

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