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Macrophage transcription factor TonEBP promotes systemic lupus erythematosus and kidney injury via damage-induced signaling pathways

Thus, TLR2/TLR4 activation promotes the dissociation of the inhibitor of nuclear factor kappa-B (I-B)/NF-B complex through a myeloid differentiation primary response 88-dependent (MyD88) signaling pathway, mediating the nuclear translocation of nuclear factor kappaB (NF-B) and specifically acting on the NLRP3 and IL-1B gene promoter regions

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1897.R1) and with the IRB committee, Al Yousif Hospital, Alkhobar, Saudi Arabia, (AYH IRB: 02/03/2023)

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