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doi: 10.1371/journal.pone.0040156 70 MrozPAFinanBGelfanovVYangBTschpMHDiMarchiRDet al

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Space sessions 12 weeks apart for an initial series, transitioning to monthly maintenance once results are established

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Retratrutide vs Other GLP-1/GIP Drugs Retatrutides half-life places it in the same pharmacokinetic class as other long-acting incretin drugs, but its triple agonist mechanism sets it apart in terms of outcomes

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Yu X, Nguyen P, Burns NC, et al

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Additionally, obesity and IR both contribute to -cell dysfunction and apoptosis, mechanistically explained by glucotoxicity and increased immunogenicity (the accelerator hypothesis) or by -cell exhaustion due to increased metabolic demand (the overload hypothesis) [23]

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