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Antcdents d'allergie aux cobalamines (vitamine B12 et substances apparentes)

Specifically, vitamin B12 helps us metabolize food, produce red blood cells, and methylate DNA (more on this later)

It is commonly used in laboratory and compounding settings as a diluent for reconstituting or diluting compatible substances under controlled conditions

We further confirmed this by immunohistochemistry, showing that LPS-treated placentas have more pH2A.X-positive cells in the labyrinth exchange region and the maternal decidua, whereas NR intervention normalized this effect to control levels (Fig 4M and N)

It increased survival of cultured enteric neurons and proliferation of enteric glial cells, suggesting direct neuroprotective effects on the enteric nervous system that could influence central serotonin tone through vagal signaling