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For the treatment groups with CuCl 2 and Cu(OAc) 2 , copper compounds had a positive correlation with the protein level regulated

In PK15 cells, using the increased expression of DNMT1 , OTA can induce nephrotoxicity ( via disrupting lipid raft formation ( Enterotoxicity Mycotoxins target the gastrointestinal tract to produce adverse effects

Researchers suggest that this could be due to the drugs causing malabsorption of folate, increasing excretion of folate in urine, and accelerating folate metabolism

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