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B12 injections may also be indicated in those with pernicious anaemia, diabetes, neuropathy, heart disease, circadian rhythm sleep disorders, memory loss, depression, fatigue, AIDS, inflammatory bowel disease (IBD), Lyme disease, osteoporosis, tendonitis, psychiatric disorders, Alzheimers disease, liver and kidney disease, and asthma
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This has also occurred in humans, such as iatrogenic Creutzfeld-Jakob disease (Brown et al., 2012), variant CJD in the context of bovine spongiform encephalopathy (Diack et al., 2014), Lewy body pathology spreading to transplanted fetal neurons (Li et al., 2008) and possibly even Alzheimers or cerebral amyloid pathology from injection with contaminated human growth hormone extracts (Purro et al., 2018
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The choice between cyanocobalamin and hydroxocobalamin might also depend on the neurological symptoms