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At the more speculative end of the spectrum are metabolically healthy adults using low-dose GLP-1s for longevity, inflammation control, cognitive performance, or broader optimization goals

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In a randomized controlled trial, Falutz et al., New England Journal of Medicine (2010) found that Tesamorelin significantly reduced VAT in HIV-infected patients with abdominal fat accumulation, leading to a healthier body composition and reduced cardiometabolic risk

31 and Alanazi et al