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Synthetic cathinones also impair mitochondrial function, reduce ATP production, and increase the opening of mitochondrial permeability transition pores

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Classical acyltransferases (KAT family) and deacylases (HDAC and SIRT family) are believed to catalyze all lactylation modifications and delactylation processes, but several non-classical acyltransferases are also included, such as AARS1, AARS2 (Fig