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It helps lower LDL cholesterol while raising HDL cholesterol, and some research has shown positive effects on immune function, including reduced frequency of cold and flu

Cell 178 , 850866.e26 (2019)

And when he wrote that book, I met him like eight months later and he told me a story and I've rarely told told people about this, but I'll put this on your podcast

GLP-1 receptors are expressed on up to 70% cerebral arterioles [18] and endothelial cells, and experimental models demonstrate that GLP-1 signaling promotes arteriolar vasodilation, improved endothelial nitric oxide signaling, and angiogenic pathways such as VEGF upregulation, all of which enhance nutrient and oxygen delivery to metabolically active brain regions [13,14]

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Extended-release formulations (Mucinex DM, 12-hour) carry higher risk of side effects because they deliver larger doses over timenever crush or chew these tablets