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(71) found that intake of vitamin D was associated with slower rates of cognitive decline over time

Consequently, tissue-level outcomes may depend not only on receptor activation but also on the availability of metabolic substrates required to sustain bioenergetic and redox balance under conditions of reduced nutrient inflow

doi:10.1039/c1pp05219e

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Comparatively, tirzepatide, the active ingredient in Zepbound and Mounjaro, demonstrated an average weight loss of 22.9% at 176 weeks with the 15 mg dose in the SURMOUNT-1 Phase 3 study in adults with pre-diabetes and obesity or overweight