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Glucagon signalling, classically associated with raising blood glucose, also stimulates lipolysis in adipose tissue, increases mitochondrial activity in hepatocytes, and promotes whole-body energy expenditure

The evaluation ensures that therapy is tailored safely to the individuals health profile and treatment goals

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1 Results from the trial were presented at ObesityWeek 2025 and simultaneously published in The Lancet

The clinical record must clearly demonstrate the providers active oversight and the medical necessity of the prolonged treatment

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