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Sex and race differences of cerebrospinal fluid metabolites in healthy individuals

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.Through randomized trials, their broad impact has been unequivocally proven for diabetes, obesity, and for treating related conditions of heart failure (with preserved ejection fraction), kidney disease, liver disease, sleep apnea, along with unexpected suppression of addiction to alcohol, cigarette smoking, nail biting and gambling

In 1947, Leon M Meyer described the results of his study on a small number of pernicious anemia patients with positive hematological responses resulting from the intake of very high doses of folic acid (2050 mg/d) (10)

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