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Because providers understand the absorption limitations, many prescribe significantly higher daily doses of oral tirzepatide compared to the weekly injectable dose

Metabolism 49 , 709717 (2000)

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Consistent with the effects of GCGR in increasing lipolysis and thermogenesis besides elevating blood glucose levels, preclinical studies have found that peptide 20 improved energy metabolism and hepatic lipid handling without exacerbating preexisting hyperglycemia 22

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