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Melanie Cree, MD, PhD, a pediatric endocrinologist and lead author, explicated the clinical conundrum wherein patients often endure a fragmented treatment approach

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Systemic inflammation is particularly important because it influences metabolism, immune signaling, cardiovascular health, and even skin quality

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I am a big believer in medication, and I think that we have been advocating for lifestyle change for a long time and havent made a whole lot of progress. In a 2023 randomized controlled trial of semaglutide involving adolescents ages 13 to 17 with a BMI at or above the 95th percentile, 44 percent of the teens taking the drug recorded a drop in BMI so significant they were reclassified as being normal weight or overweight, rather than obese