PubMed Systematic reviewGLP-1 class evidence2025 Discontinuing glucagon-like peptide-1 receptor agonists and body habitus Used for pages discussing stopping therapy, weight regain, and long-term planning
Uniquely, MOTS-c has been observed to translocate from the mitochondria to the nucleus in response to metabolic stress
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More recently, irritability has also been recognised as a core antecedent of depression in young people 7 , therefore playing an important etiological role in the development of depressive states