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Since such a structure could not explain a high stability constant of the GHK-Cu complex (log 10 = 16.44 versus 8.68 of the GH copper complex, which is similar to the GHK-Cu structure), it was proposed that another amino group participates in the complex formation

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Similar results were obtained when APEX2 was expressed in the mitochondrial matrix instead of the cytosol (Extended Data Fig

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In the absence of GliT, DTG fluxes via GtmA to BmGT, which results in both SAM depletion and SAH overproduction