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Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities

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The fact that it showed significant neuroprotection when administered just 30 seconds after ischemia suggests a rapid mechanism of action, which is critical in the narrow therapeutic windows that characterize acute brain injury

Avoid concurrent use with immunosuppressants, certain cancer therapies, or high-dose corticosteroids unless under medical supervision

Marques J, Fernandez-Irigoyen J, Ainzua E, Martinez-Azcona M, Cortes A, Roncal C, Orbe J, Santamaria E, Zalba G (2022) NADPH oxidase 5 (NOX5) overexpression promotes endothelial dysfunction via cell apoptosis, migration, and metabolic alterations in human brain microvascular endothelial cells (hCMEC/D3)