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Levels decline with age, chronic stress, and ongoing exposure to environmental demands

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Watch for reduced urination, swelling in the ankles or legs, fatigue, or shortness of breath

It is a known fact that eNOS-derived NO is essential in angiogenesis by enhancing vascular endothelial growth factors and up-regulating the recruitment of endothelial progenitor cells from the bone marrow [142, 143]

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