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When these two genes were exogenously expressed in human intestinal organoids, an increase in BMX or HCK was observed to significantly improve the number and size of organoid hyperplasia within the organoid lumen, as well as multiple polyp bud protrusions and wall hyperplasia

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In clinical trials, retatrutide at the 12mg dose produced greater average weight loss (24.2-28.7%) than tirzepatide at 15mg (~18%)

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Potassium levels: In severe anemia, rapid red cell production can lower potassium