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Therefore, as an autoimmune disease, GD can cause systemic immune activation and high levels of inflammatory factors in the circulation, leading to the activation of the HPA axis and hypersecretion of related hormones

It also has potent antioxidant and anti-inflammatory effects, reducing oxidative stress in gingival and joint tissue

Some researchers experience injection site reactions including redness, swelling, or itching, which are typically mild and resolve on their own

Based on these findings, KEGG enrichment analysis further showed that irradiation mainly affected multiple signaling pathways related to inflammatory responses, apoptosis, and epithelial barrier damage, while EGCG-Zn treatment reversed these changes at the transcriptional level (Figs

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Nevertheless, it remains unknown whether hydrochlorothiazide or thiazide-like diuretics reduce GLP-1 responses, glucose tolerance, energy intake behavior and feeding patterns in the long term