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Jacques PF, Selhub J, Bostom AG, Wilson PW, Rosenberg IH

On the primary endpoint, a standard clinical dementia rating, semaglutide was no better than placebo at slowing progression

Mandal et al

doi:10.1212/CPJ.0000000000000043 Interlaminar route: In this technique, the needle is inserted from the back of the spine and the medication is deposited into the epidural space

Mitochondrial derived peptide MOTS-c prevents the development of heart failure under pressure overload conditions in mice

Osteoarthritis is also biologically heterogeneous, involving cartilage, bone, synovium, nerves, and systemic metabolic factors rather than a single disease pathway. Mandelbaum said there are lifestyle factors people can adopt to help lower the risk of osteoarthritis as well as its painful effects