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The physiological relevance of the mesolimbic GLP-1 is suggested by the demonstration that similar anorexic effects can be obtained by independent stimulation of the mesolimbic and hypothalamic GLP-1 receptors (GLP-1R)

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DOI: 10.1186/s40360-017-0172-3 [Google Scholar] Li W, Cui M, Wei Y, Kong X, Tang L, Xu D

Impact of dopamine oxidation on dopaminergic neurodegeneration

Many patients benefit from physician-guided medical weight loss programs that combine: Nutritional counseling Lifestyle modifications Exercise recommendations Behavioral support Prescription medications when appropriate Medical weight loss can be a good option for individuals who do not meet bariatric surgery criteria or who prefer to begin with a non-surgical approach