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An analysis of the free energy minima and maxima for the water probe in subpockets A-C using SZMAP 37 and WaterOrientation extension in VIDA 40 is shown in Fig

Epub 2019 Aug 1

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Due to its efficiency, flexibility, and operability, combining proximity labeling with existing techniques can solve biological problems that are currently difficult to address, providing effective support for drug target discovery, cancer diagnosis, single-cell proteomics, and other research fields