retatrutide eli lilly phase 2 results Shows Promising in Obesity and Diabetes Treatment | Mina Gereis posted on the topic Eli Lilly's Retatrutide Shows Promising

Ignoring persistent symptoms often delays effective treatment

This effect stems from weight loss itself combined with possible direct vascular effects

The weight loss mechanism involves coordinated effects on multiple metabolic pathways

Importantly, they noted that these mental health improvements had not occurred when they had achieved this level of weight loss in the past through other means e.g

In a study comprising 16 patients with T2DM and 12 non-diabetic controls, flow-mediated vasodilation was enhanced in both groups by GLP1 infusion of 0.4 pmol/kg/min, administered during a 2-hour hyperglycemic clamp [106]

The systemic effect observed in mice was then confirmed in cultured human heart cells