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In -syn toxicity models, MANF overexpression significantly delayed neurodegeneration by correcting dopaminergic metabolic disturbances [151]

This suggests GLP-1 is a natural part of the body's own inflammatory response system, and GLP-1RAs amplify this beneficial pathway, supporting the body's inherent mechanisms for immune and metabolic balance

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After an additional twenty-four hours, cells were detached by trypsinization, washed in PBS and frozen until lipids were extracted