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McGraw-Hill / Lange rxlist.com (Januvia ) Keywords Saxagliptin Trade Name: Onglyza Mechanism of Action: a DPP-4 inhibitor, similar to Sitagliptin Pharmacokinetics: mixed renal & hepatic clearance dosage should be reduced in patients with moderate to severe renal impairment References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)