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The researchers report, There was a statistically significant difference in patient satisfaction at 45 days, 2 months, 75 days, 3 months, and 6 months following treatment. No side effects were reported in 14 of the participants, and no side effects were reported at all related strictly to the microneedling aspect of the treatment

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Y. Xionget al., Neuroprotective and neurorestorative effects of thymosin 4 treatment following experimental traumatic brain injury, Wiley, Oct. 2012. doi: 10.1111/j.1749-6632.2012.06683.x