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Arch Hyg Rad Toksikol 63(4):417427

Uncovering the functional link between SHANK3 deletions and deficiency in neurodevelopment using iPSC-Derived human neurons

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The most commonly reported side effects are mild and transient: injection site redness or minor bruising, transient fatigue in the first one to two weeks, and occasionally mild headache following the first few injections, a pattern sometimes attributed to the acute shift in cellular energy metabolism as AMPK pathways are upregulated [3]