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If infection is evident, anti-inflammatory and antibiotic treatments are necessary

Chronic elevation of cortisol levels , as seen in Cushing's syndrome, is associated with multiple adverse effects including: Central obesity and metabolic syndrome Insulin resistance and type 2 diabetes Hypertension and cardiovascular disease Osteoporosis and increased fracture risk Mood disturbances, anxiety, and depression Impaired immune function and wound healing Psychological stress can affect cortisol patterns, though the relationship is complex and varies between individuals

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or MCE, HY-108467) was diluted in sterile saline and injected at the indicated concentrations

J Neurosci 2019;39:72067217.ArticlePubMedPMC 71