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These include liraglutide (Saxenda) and semaglutide (Wegovy), representing an expansion beyond their original diabetes indication and highlighting the broader metabolic impact of GLP-1 pathway activation

What are the main side effects, and who is a good candidate for this program

However, these findings remain preliminary, inconsistent across studies, and have not been robustly demonstrated in well-designed human clinical trials

This article belongs to a Special Issue on In Memory of Klaus Miczek

Phase 1 running since June 2022 with no new public milestone

In the SCALE study, liraglutide, administered daily at a dose of 0.63.0 mg, was associated with a body weight loss 5.6 kg greater than placebo [45]