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Apart from A plaques and NFTs, other pathological features of AD include neuroinflammation and microglial activation, synaptic dysfunction, reduced cerebral glucose metabolism, astrocyte activation, and neuronal loss [4]

Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2

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Brennan IM, Feltrin KL, Horowitz M, Smout AJ, Meyer JH, Wishart J et al

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After treatment, each sample (100 L) was mixed with 40 L of SP3 beads mix (20 L of hydrophobic + 20 L of hydrophilic beads), incubated for 15 min and then overlayed with 1 mL of absolute EtOH