Patients with pre-existing gastrointestinal conditions, those who have undergone bariatric surgery (who typically require specific bariatric-formulation supplements), or individuals following restrictive diets (vegetarian, vegan) may enter GLP-1 treatment with suboptimal nutrient status
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As weight starts to come off, there is one common pitfall that often gets overlooked: not all the weight you lose is fat
Moreover, elevated insulin levels resulting from hyperinsulinemia trigger insulin-like growth factor (IGF) signaling, activating key pathways such as phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK) [26]
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