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A drug originally designed to combat a life-threatening disease is now being used casually, sometimes without proper medical supervision

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This does not mean retatrutide is better or more suitable than existing licensed treatments

There is no FDA-approved patch for a GLP-1, says Natasha Bhuyan, MD, a board-certified family physician at Amazon One Medical in Phoenix

Weight Reduction at 48 Weeks : 1 mg group: 8.7% mean weight loss

On 21 May 2026 , Lilly published the long-awaited topline results from the TRIUMPH-1 Phase 3 trial, and the data is striking: participants on the highest dose lost an average of 28.3% of their body weight at 80 weeks , with 45.3% of patients losing 30% or more a threshold previously only achievable with bariatric surgery