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The capillary network formation was determined using a Zeiss Microscope associated with a Nikon camera (Axio Observer A1, Zeiss) and quantified with ImageJ software (U.S

, 2024), and the study by Hanif et al

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Furthermore, future research should prioritize exploring synergistic combinations of such genetic interventions with pharmacological modulators of autophagy or ferroptosis to achieve enhanced therapeutic efficacy