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In rodent models, GLP-1 also enhances modest beta cell mitogenesis and inhibits apoptosis thereby leading to enhanced beta cell mass (13, 107, 135)

Action of GLP-1 on the pancreas Physiology of GLP-1 as an incretin The primary action of GLP-1 for lowering blood glucose is the stimulation of insulin secretion by potentiating the action of glucose (20, 74, 80, 125)

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The AUC(0-) values were 4.38, 9.75, 13.59, and 18.22 g h/mL, and the elimination t1/2 averaged 2.14, 2.59, 2.62, and 2.69 h, respectively (Xu et al., 2013)