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Their resistance has been linked to their capacity to reduce ROS levels through the accumulation of intracellular antioxidants like glutathione and the induction of GCL, as demonstrated in breast and liver TICs [18,19,20]

doi: 96

Metabolic reprogramming in melanoma therapy

doi: 10.3390/biology11020159 21 Beltrn-GarcaJ.Osca-VerdegalR.PallardF

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In a study involving rats, researchers found a decrease in this gene due to methylation, a chemical tag that reduces gene activity